GeniusPure Alpha-GPC: Premier Alpha-GPC by NNB Nutrition

Alpha-GPC has become increasingly popular in the sports nutrition industry, and for good reason. Known for its powerful nootropic properties, Alpha-GPC serves as a precursor to the neurotransmitter acetylcholine, which plays a crucial role in learning, memory, and cognitive function. This makes it one of the most sought-after focus-enhancing ingredients in supplements today.
However, not all Alpha-GPC supplements are created equal. While it’s widely used for its cognitive and performance benefits, the quality and effectiveness can vary significantly depending on the form used. Before diving into the concerns surrounding generic Alpha-GPC, let’s first explore the critical connection between acetylcholine and Alpha-GPC—and why it matters for both brain function and athletic performance.
The Impact of Alpha-GPC on Sports Nutrition and Athletic Performance
After consumption, Alpha-GPC is converted into phosphorylcholine, which then serves as a key choline source for acetylcholine synthesis. Research on cognitive health, particularly in individuals with dementia or cerebrovascular conditions, has shown that Alpha-GPC supplementation may lead to notable improvements in cognitive function when compared to a placebo.
Beyond its cognitive benefits, acetylcholine plays a crucial role in muscle function, acting as the neurotransmitter responsible for triggering muscle contractions. Because of this, Alpha-GPC has been suggested to enhance power and strength, particularly in activities that involve intense muscular contractions. The theory is that higher acetylcholine levels—a result of Alpha-GPC supplementation—may lead to stronger muscle contraction signals, ultimately improving force production.
Recent studies have examined the impact of Alpha-GPC supplementation at doses of 150 mg and 300 mg, showing potential improvements in reaction time and vertical jump power. These findings suggest that Alpha-GPC could be a valuable addition to sports performance supplements, particularly for athletes looking to optimize explosiveness, strength, and cognitive function.
GeniusPure Alpha-GPC: Scientifically Proven Benefits for Brainpower and Performance
In 2024, NNB Nutrition conducted a gold-standard clinical study on GeniusPure Alpha-GPC, using a randomized, double-blind, placebo-controlled, crossover design with 20 resistance-trained males. The study evaluated cognitive performance, exercise performance, and safety across three conditions: placebo, 350 mg GeniusPure, and 700 mg GeniusPure.
Cognitive Benefits
- Focus & Decision-Making: Alpha-GPC enhanced attention (108% increase in focus), reduced distractions, and improved processing speed.
- Stroop Test Performance: Total scores increased by 150% (high dose) and 108% (low dose) vs. placebo.
- Processing Speed: 140% faster (high dose) and 50% faster (low dose) vs. placebo.
- Alertness: Participants reported a 16.7% boost in alertness compared to placebo.
Exercise Performance
- Upper-Body Strength: High-dose Alpha-GPC significantly increased peak force (p = 0.043).
- Lower-Body Strength: Low-dose Alpha-GPC outperformed the high dose in peak force production.
- Power & Force Production: 2.5–10% improvements in upper- and lower-body performance vs. placebo.
Key Takeaway
GeniusPure Alpha-GPC is clinically proven to enhance cognitive function, increase alertness, and boost athletic performance, making it a powerful tool for both mental and physical optimization.
The Problem with Generic Alpha-GPC: Quality, Absorption, and Effectiveness
The primary issue with generic Alpha-GPC is its hygroscopic nature, meaning it readily absorbs moisture from the air. Over time, this leads to clumping and, in extreme cases, solidification, rendering the product ineffective. To combat this, most Alpha-GPC formulations include stabilizing agents like silica, which is why you'll often see Alpha-GPC listed with a percentage yield, typically 50% Alpha-GPC by mass.
However, this stabilization process comes with its own challenges. The added ingredients increase the mass and volume of the product, which can raise production costs due to larger tub sizes, label requirements, and shipping expenses. It also creates dosing difficulties for capsules, as the bulkier formulation requires larger or more capsules to meet clinical dosage recommendations. Additionally, the body must process these stabilizers alongside the active ingredients, which may impact absorption efficiency.
While Alpha-GPC remains a highly effective ingredient for cognitive and athletic performance, generic versions present significant formulation challenges. This is where NNB Nutrition’s GeniusPure steps in, offering a more stable and efficient alternative.
Why GeniusPure Alpha-GPC May Be the Best Alpha-GPC Ingredient on the Market
The main benefit of NNB Nutrition's GeniusPure Alpha-GPC is its superior hygroscopic stability, outperforming any other Alpha-GPC ingredient available. Unlike generic versions that rapidly absorb moisture and degrade over time, GeniusPure maintains its integrity for significantly longer.
NNB offers two versions of GeniusPure: 70% yield and 90% yield, with the 70% yield providing even greater stability against moisture absorption. In a controlled stability test, NNB compared generic 50% Alpha-GPC to 90% GeniusPure Alpha-GPC in a room set at 86°F (30°C). The results? Within just 60 minutes, the generic Alpha-GPC showed heavy clumping, while GeniusPure remained noticeably more stable.
These findings highlight GeniusPure Alpha-GPC’s superior shelf life and performance, making it the gold standard for both cognitive and athletic supplementation while also somehow managing to pack an even larger percent yield of Alpha-GPC into their ingredient.




Results of the hygroscopicity test conducted by NNB, comparing 50% generic Alpha-GPC to 90% GeniusPure Alpha-GPC.
Final Thoughts: Why GeniusPure Alpha-GPC is Revolutionary
Alpha-GPC plays a crucial role in cognitive and muscle function by serving as a key choline source for acetylcholine production. Research suggests it may improve cognitive performance, reaction time, and strength, making it a valuable supplement for both mental and physical performance. However, generic Alpha-GPC is highly hygroscopic, leading to stability issues that impact effectiveness and formulation costs. NNB Nutrition’s GeniusPure Alpha-GPC addresses these challenges by offering a more stable and efficient alternative, available in 70% and 90% yield versions. GeniusPure offers significant formulation advantages over generic Alpha-GPC due to its higher purity and greater yield, allowing for smaller, more efficient doses. Clinical studies have demonstrated its benefits, including enhanced focus (108% increase), processing speed, alertness, and improved athletic performance, solidifying GeniusPure as a top-tier option for cognitive and athletic performance.
About the Author
I’m Sammy—Cardiac Nurse, Product Formulator for Apollon Nutrition, Content Creator, and Founder of GOATED. My passion lies in helping others take control of their health through education, transparency, and honest supplement reviews. Whether it’s breaking down complex ingredients, formulating cutting-edge products, or creating engaging content, my ultimate goal is to empower individuals with the knowledge they need to make informed decisions and build a healthier lifestyle.
References
- Marcus L, Soileau J, Judge LW, Bellar D. Evaluation of the effects of two doses of alpha glycerylphosphorylcholine on physical and psychomotor performance. J Int Soc Sports Nutr. 2017 Oct 5;14:39. doi: 10.1186/s12970-017-0196-5. PMID: 29042830; PMCID: PMC5629791.
- Ziegenfuss T, Landis J, Hofheins J. Acute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to, and peak force production during, resistance exercise. J Int Soc Sports Nutr. 2008 Sep 17;5(Suppl 1):P15. doi: 10.1186/1550-2783-5-S1-P15. PMCID: PMC3313098.
- @inproceedings{Cruse2018TheAE, title={The Acute Effects Of Alpha-Gpc On Hand Grip Strength, Jump Height, Power Output, Mood, And Reaction-Time In Recreationally Trained, College-Aged Individuals}, author={Joseph Cruse}, year={2018}, url={https://api.semanticscholar.org/CorpusID:87215645}}
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