Overview

What is Uridine-5'-Monophosphate? Uridine-5'-Monophosphate is a natural nucleotide base that plays an extensive role in the central nervous system. There are several different forms of uridine available on the market, but Uridine-5'-Monophosphate is the most bioavailable and researched. The benefits of Uridine-5'-Monophosphate are well documented; it maintains the fatty membranes of synaptic cells and also aids in creating connections between neurons. In a placebo-controlled trial conducted in 2011, results showed that subjects who received 1000mg uridine twice daily overt the course of a week had higher levels of brain phospholipids when compared to the placebo controlled group. Phospholipids protect neurons and play important roles in the structure of cell membranes and cell functions.

Uridine-5'-Monophosphate has the ability to activate the P2Y2 receptors in the brain. P2Y2 plays a crucial role in modulating the brain and also helps to increase acetylcholine levels; a neurotransmitter responsible for increases in focus, cognition, and muscle contractions. P2Y2 also enhances neuroplasticity via NGF (nerve growth factor).

There is also limited literature that suggests Uridine-5'-Monophosphate may improve sleep scores. Results from these studies would benefit from further research.

Many individuals stack Uridine-5'-Monophosphate with a Fish Oil supplement and acetylcholine precursor such as Alpha-GPC or Citicholine to further boost overall cognition.

The benefits of Uridine-5'-Monophosphate are plentiful. For more information, read here https://examine.com/supplements/uridine/

Applications

Uridine-5-Monophosphate is typically found within pre-workout, focus, and sleep products.

Benefits of Uridine-5'-Monophosphate

Improves:

• Connections between neurons
• Cognition
• Positive Mood
• Sleep Scores

Recommended Dose

50-1000mg per day

Supplements